Evaluation of Ovarian Cancer: Initial Application of Coregistered Photoacoustic Tomography and US.

ABSTRACT: Purpose To assess transvaginal coregistered photoacoustic tomography (PAT) and pulse-echo US for diagnosis of ovarian cancer based on functional parameters provided by PAT. Materials and Methods Between February 2017 and December 2017, 26 ovarian masses from 16 participants were successfully imaged in vivo by multispectral photoacoustic imaging, including nine invasive epithelial ovarian cancers (six serous carcinomas and three endometroid adenocarcinomas), three other tumors (two borderline serous tumors and one sex cord-stromal tumor), and 14 benign and normal (hereafter referred to as benign/normal) ovaries. The relative total hemoglobin concentration (rHbT) and mean oxygen saturation (sO₂) shown at PAT were used to characterize the ovaries identified at US. Results The avera

SUBMITTER: Nandy S 

PROVIDER: S-EPMC6283286 | biostudies-literature | 2018 Dec

REPOSITORIES: biostudies-literature