Prostate cancer screening with prostate-specific antigen (PSA) test: a systematic review and meta-analysis.

ABSTRACT:

Objective

To investigate the efficacy and safety of prostate-specific antigen (PSA) testing to screen for prostate cancer.

Design

Systematic review and meta-analysis.

Data sources

Electronic search of Cochrane Central Register of Controlled Trials, Web of Science, Embase, Scopus, OpenGrey, LILACS, and Medline, and search of scientific meeting abstracts and trial registers to April 2018.

Eligibility criteria for selecting studies

Randomised controlled trials comparing PSA screening with usual care in men without a diagnosis of prostate cancer.

Data extraction

At least two reviewers screened studies, extracted data, and assessed the quality of eligible studies. A parallel guideline committee (BMJ Rapid Recommendation) provided input on the design an

SUBMITTER: Ilic D 

PROVIDER: S-EPMC6283370 | biostudies-literature | 2018 Sep

REPOSITORIES: biostudies-literature