Baroreflex function, haemodynamic responses to an orthostatic challenge, and falls in haemodialysis patients.

ABSTRACT:

Background

Stage 5 chronic kidney disease patients on haemodialysis (HD) often present with dizziness and pre-syncopal events as a result of the combined effect of HD therapy and cardiovascular disease. The dysregulation of blood pressure (BP) during orthostasis may be implicated in the aetiology of falls in these patients. Therefore, we explored the relationship between baroreflex function, the haemodynamic responses to a passive orthostatic challenge, and falls in HD patients.

Methods

Seventy-six HD patients were enrolled in this cross-sectional study. Participants were classified as "fallers" and "non-fallers" and completed a passive head up tilting to 60o (HUT-60°) test on an automated tilt table. ECG signals, continuous and oscillometric BP measurements and impedance ca

SUBMITTER: Zanotto T 

PROVIDER: S-EPMC6283578 | biostudies-literature | 2018

REPOSITORIES: biostudies-literature