Multiscale modelling of the human lumbar facet capsular ligament: analysing spinal motion from the joint to the neurons.

ABSTRACT: Due to its high level of innervation, the lumbar facet capsular ligament (FCL) is suspected to play a role in low back pain (LBP). The nociceptors in the lumbar FCL may experience excessive deformation and generate pain signals. As such, understanding the mechanical behaviour of the FCL, as well as that of its underlying nerves, is critical if one hopes to understand its role in LBP. In this work, we constructed a multiscale structure-based finite-element (FE) model of a lumbar FCL on a spinal motion segment undergoing physiological motions of flexion, extension, ipsilateral and contralateral bending, and ipsilateral axial rotation. Our FE model was created for a generic FCL geometry by morphing a previously imaged FCL anatomy onto an existing generic motion segment model. The fibre organi

SUBMITTER: Zarei V 

PROVIDER: S-EPMC6283995 | biostudies-literature | 2018 Nov

REPOSITORIES: biostudies-literature