Space-time heterogeneity of hand, foot and mouth disease in children and its potential driving factors in Henan, China.

ABSTRACT:

Background

Hand, foot and mouth disease (HFMD) has become a substantial threat recently. However few studies have quantified spatiotemporal heterogeneity of HFMD and detected spatiotemporal interactive effect of potential driving factors on this disease.

Methods

Using GeoDetector and Bayesian space-time hierarchy model, we characterized the epidemiology of HFMD in Henan, one of the largest population provinces in China, from 2012 to 2013, and quantified the impacts of potential driving factors.

Results

Notably, 21.43 and 24.60% counties were identified as hot and cold spots, respectively. Spatially, the hotspots were mainly clustered in regions where the economic level was high. Temporally, the highest incidence period of HFMD was discovered to be in late spring and e

SUBMITTER: Zhang X 

PROVIDER: S-EPMC6286567 | biostudies-literature | 2018 Dec

REPOSITORIES: biostudies-literature