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Vasoplegia after implantation of a continuous flow left ventricular assist device: incidence, outcomes and predictors.


ABSTRACT:

Background

Vasoplegia after routine cardiac surgery is associated with severe postoperative complications and increased mortality. It is also prevalent in patients undergoing implantation of pulsatile flow left ventricular assist devices (LVAD). However, less is known regarding vasoplegia after implantation of newer generations of continuous flow LVADs (cfLVAD). We aim to report the incidence, impact on outcome and predictors of vasoplegia in these patients.

Methods

Adult patients scheduled for primary cfLVAD implantation were enrolled into a derivation cohort (n = 118, 2006-2013) and a temporal validation cohort (n = 73, 2014-2016). Vasoplegia was defined taking into consideration low mean arterial pressure and/or low systemic vascular resistance, preserved cardiac index an

SUBMITTER: de Waal EEC 

PROVIDER: S-EPMC6286572 | biostudies-literature | 2018 Dec

REPOSITORIES: biostudies-literature