Genotyping methods and molecular epidemiology of Mycobacterium avium subsp. paratuberculosis (MAP).

ABSTRACT: Mycobacterium avium subsp. paratuberculosis (MAP) is the causative agent of Johne's disease (JD) which affects mainly ruminants and is characterized by chronic diarrhea and emaciation. Johne's disease is highly prevalent in many countries around the world and leads to high economic losses associated with decreased production. Genotyping of the involved pathogen could be used in the study of population genetics, pathogenesis and molecular epidemiology including disease surveillance and outbreak investigation. Principally, researchers have first assumed the presence of two different MAP strains that are associated with the animal host species (cattle and sheep). However, nowadays MAP characterization depends mainly upon genetic testing using genetic markers such as insertion elements, repeti

SUBMITTER: Fawzy A 

PROVIDER: S-EPMC6286618 | biostudies-literature | 2018 Dec

REPOSITORIES: biostudies-literature