Sex Differences in the Association between Night Shift Work and the Risk of Cancers: A Meta-Analysis of 57 Articles.

ABSTRACT:

Objectives

To identify the association between night shift work and the risk of various cancers with a comprehensive perspective and to explore sex differences in this association.

Methods

We searched PubMed, Embase, and Web of Science for studies on the effect of night shift work on cancer, including case-control, cohort, and nested case-control studies. We computed risk estimates with 95% confidence intervals (CIs) in a random or fixed effects model and quantified heterogeneity using the I ² statistic. Subgroup, metaregression, and sensitivity analyses were performed to explore potential sources of heterogeneity. Contour-enhanced funnel plots and the trim and fill method were used together to analyze bias. Linear dose-response analysis was used to quantit

SUBMITTER: Liu W 

PROVIDER: S-EPMC6287141 | biostudies-literature | 2018

REPOSITORIES: biostudies-literature