Current Practice and Emerging Molecular Imaging Technologies in Oral Cancer Screening.

ABSTRACT: Oral cancer is one of the most common cancers globally. Survival rates for patients are directly correlated with stage of diagnosis; despite this knowledge, 60% of individuals are presenting with late-stage disease. Currently, the initial evaluation of a questionable lesion is performed by a conventional visual examination with white light. If a lesion is deemed suspicious, a biopsy is taken for diagnosis. However, not all lesions present suspicious under visual white light examination, and there is limited specificity in differentiating between benign and malignant transformations. Several vital dyes, light-based detection systems, and cytology evaluation methods have been formulated to aid in the visualization process, but their lack of specific biomarkers resulted in high false-positive

SUBMITTER: Strome A 

PROVIDER: S-EPMC6287312 | biostudies-literature | 2018 Jan-Dec

REPOSITORIES: biostudies-literature