Coverage and timeliness of vaccination and the validity of routine estimates: Insights from a vaccine registry in Kenya.

ABSTRACT:

Background

The benefits of childhood vaccines are critically dependent on vaccination coverage. We used a vaccine registry (as gold standard) in Kenya to quantify errors in routine coverage methods (surveys and administrative reports), to estimate the magnitude of survivor bias, contrast coverage with timeliness and use both measures to estimate population immunity.

Methods

Vaccination records of children in the Kilifi Health and Demographic Surveillance System (KHDSS), Kenya were combined with births, deaths, migration and residence data from 2010 to 17. Using inverse survival curves, we estimated up-to-date and age-appropriate vaccination coverage, calculated mean vaccination coverage in infancy as the area under the inverse survival curves, and estimated the proportion of

SUBMITTER: Adetifa IMO 

PROVIDER: S-EPMC6288063 | biostudies-literature | 2018 Dec

REPOSITORIES: biostudies-literature