Tofacitinib for refractory uveitis and scleritis.

ABSTRACT:

Purpose

To report the successful use of tofacitinib in the treatment of refractory uveitis and scleritis.

Observations

Two patients, one with scleritis and another with anterior and intermediate uveitis, presented with refractory disease after failure of multiple steroid-sparing therapies. Treatment with tofacitinib led to durable resolution of uveitis and scleritis.

Conclusions and importance

Tofacitinib is a potential novel treatment option for refractory, noninfectious inflammatory eye disease.

SUBMITTER: Paley MA 

PROVIDER: S-EPMC6288302 | biostudies-literature | 2019 Mar

REPOSITORIES: biostudies-literature