Reproducible model development in the cardiac electrophysiology Web Lab.

ABSTRACT: The modelling of the electrophysiology of cardiac cells is one of the most mature areas of systems biology. This extended concentration of research effort brings with it new challenges, foremost among which is that of choosing which of these models is most suitable for addressing a particular scientific question. In a previous paper, we presented our initial work in developing an online resource for the characterisation and comparison of electrophysiological cell models in a wide range of experimental scenarios. In that work, we described how we had developed a novel protocol language that allowed us to separate the details of the mathematical model (the majority of cardiac cell models take the form of ordinary differential equations) from the experimental protocol being simulated. We deve

SUBMITTER: Daly AC 

PROVIDER: S-EPMC6288479 | biostudies-literature | 2018 Nov

REPOSITORIES: biostudies-literature