Placental concentrations of essential, toxic, and understudied metals and relationships with birth outcomes in Chattanooga, TN.

ABSTRACT:

Background

Comprehensive examinations of placental metal concentrations and correlations with infant parameters are under-investigated. Chattanooga, Tennessee's consistently high incidence of low birth weight and potential for metal exposure provides an ideal opportunity to investigate potential correlations.

Objectives

To investigate the associations between a wide variety of metals in placental tissue and multiple infant parameters.

Methods

A total of 31 elements were screened via ICP-MS in 374 individual placental samples. Of those, 14 were quantifiable in > 86% of the samples. We examined correlations between metal concentrations and infant parameters (birth weight, gestational age, birth weight centile, placental weight, birth length and head circumference). We f

SUBMITTER: Mikelson CK 

PROVIDER: S-EPMC6288679 | biostudies-literature | 2019 Jan

REPOSITORIES: biostudies-literature