Repeat Infective Endocarditis in Persons Who Inject Drugs: "Take Another Little Piece of my Heart".

ABSTRACT:

Background

Injection drug use (IDU) is a major risk factor for infective endocarditis (IE). Few data exist on repeat IE (rIE) in persons who inject drugs (PWID).

Methods

Patients ≥18 years old seen at Wake Forest Baptist Medical Center from 2004 to 2017 who met Duke criteria for IE and who self-reported IDU in the 3 months before admission were identified. The subset of PWID who developed rIE, defined as another episode of IE at least 10 weeks after diagnosis of the first episode, was then reviewed.

Results

Of the 87 PWID who survived their first episode of IE, 22 (25.3%) experienced rIE and 77.3% had rIE within a year of the first episode. All patients who experienced rIE resumed IDU between episodes of IE. Of the patients with rIE, 54.5% had an infection caused by <

SUBMITTER: Huang G 

PROVIDER: S-EPMC6288769 | biostudies-literature | 2018 Dec

REPOSITORIES: biostudies-literature