Fluorescent ZnS Quantum Dots-Phosphoethanolamine Nanoconjugates for Bioimaging Live Cells in Cancer Research.

ABSTRACT: Many human diseases, including metabolic, immune, and central nervous system disorders, as well as several types of cancers, are the consequence of an important alteration in lipid-related metabolic biomolecules. Although recognized that one of the most important metabolic hallmarks of cancer cells is deregulation of lipid metabolism, the multiple complex signaling pathways are poorly understood yet. Thus, in this research, novel nanoconjugates made of ZnS quantum dots (QDs) were directly synthesized in aqueous media using phosphoethanolamine (PEA) as the capping ligand, which is an important biomolecule naturally present in cells for de novo biosynthesis of fatty acids and phospholipids involved in the cell structure (e.g., membrane), differentiation, and cancer growth. These QD-PEA bio-n

SUBMITTER: Mansur AAP 

PROVIDER: S-EPMC6288785 | biostudies-literature | 2018 Nov

REPOSITORIES: biostudies-literature