Hormone variability and hot flash experience: Results from the midlife women's health study.

ABSTRACT:

Objective

Hot flashes are believed to be related to hormonal changes. However, the relationship between hormonal fluctuations and hot flashes has not been studied. The objective of this study is to determine hormone measurement summaries that best explain the incidence of hot flashes in midlife women.

Study design

In a cohort study of 798 midlife women over 1-7 years, women provided 4 weekly blood samples annually and completed a survey detailing life history, ongoing behaviors, and menopausal symptoms. Estradiol, progesterone, and testosterone were measured in all serum samples. Annual summary variables of each hormone were median, mean, maximum, minimum, variance, and range. The association of these values with hot flashes was assessed using multivariable logistic regressi

SUBMITTER: Chiang C 

PROVIDER: S-EPMC6289582 | biostudies-literature | 2019 Jan

REPOSITORIES: biostudies-literature