Bacterial Cohesion Predicts Spatial Distribution in the Larval Zebrafish Intestine.

ABSTRACT: Are there general biophysical relationships governing the spatial organization of the gut microbiome? Despite growing realization that spatial structure is important for population stability, interbacterial competition, and host functions, it is unclear in any animal gut whether such structure is subject to predictive, unifying rules or if it results from contextual, species-specific behaviors. To explore this, we used light sheet fluorescence microscopy to conduct a high-resolution comparative study of bacterial distribution patterns throughout the entire intestinal volume of live, larval zebrafish. Fluorescently tagged strains of seven bacterial symbionts, representing six different species native to zebrafish, were each separately monoassociated with animals that had been raised initial

SUBMITTER: Schlomann BH 

PROVIDER: S-EPMC6289661 | biostudies-literature | 2018 Dec

REPOSITORIES: biostudies-literature