Cortisol reactivity and weight gain among adolescents who vary in prenatal drug exposure.

ABSTRACT:

Objective

Low inhibitory control is linked with weight gain among youth. Inhibitory problems are associated with disruption to the hypothalamic-pituitary-adrenal axis cortisol response. Increased cortisol predicts appetite and weight gain (though may be gender specific). This study hypothesized that cortisol reactivity explains the association between inhibition and weight gain while considering the moderating factors of early stressors to the hypothalamic-pituitary-adrenal axis (e.g. prenatal-drug exposure) and gender.

Methods

Adolescents with prenatal-drug exposure (n = 76) and non-exposed comparison adolescents (NE; n = 61) completed the Conner's Continuous Performance Test and provided salivary cortisol samples. BMI z-score were measured at the initial and 12-month follo

SUBMITTER: Armstrong B 

PROVIDER: S-EPMC6289691 | biostudies-literature | 2018 Dec

REPOSITORIES: biostudies-literature