Phenotypic Characterization of Paclitaxel-Induced Peripheral Neuropathy in Cancer Survivors.

ABSTRACT:

Context

Although paclitaxel is one of the most commonly used drugs to treat breast, ovarian, and lung cancers, little is known about the impact of paclitaxel-induced peripheral neuropathy (PIPN) on cancer survivors.

Objectives

The purposes of this study were to evaluate for differences in demographic and clinical characteristics as well as measures of sensation, balance, upper extremity function, perceived stress, symptom burden, and quality of life (QOL) between survivors who received paclitaxel and did (n = 153) and did not (n = 58) develop PIPN.

Methods

Pain characteristics associated with PIPN are described in detail. Both subjective and objective measures were used to evaluate the impact of PIPN.

Results

Survivors with PIPN were significantly older, had a

SUBMITTER: Kober KM 

PROVIDER: S-EPMC6289693 | biostudies-literature | 2018 Dec

REPOSITORIES: biostudies-literature