The Effect of Statin Use on Mortality in Systemic Autoimmune Rheumatic Diseases.

ABSTRACT:

Objective

Systemic autoimmune rheumatic diseases (SARD) are associated with an increased risk of premature cardiovascular disease (CVD) and all-cause mortality. We examined the potential survival benefit of statin use among patients with SARD in a general population setting.

Methods

We conducted an incident user cohort study using a UK general population database. Our population included patients with a SARD as determined by Read code diagnoses of systemic lupus erythematosus, systemic sclerosis, Sjögren syndrome, dermatomyositis, polymyositis, mixed connective tissue disease, Behçet disease, or antineutrophil cytoplasmic antibodies-associated vasculitis between January 1, 2000, and December 31, 2014. We compared propensity score-matched cohorts of statin initiators and noni

SUBMITTER: Jorge AM 

PROVIDER: S-EPMC6289699 | biostudies-literature | 2018 Dec

REPOSITORIES: biostudies-literature