Time-Lag in Feeding Schedule Acts as a Stressor That Alters Circadian Oscillators in Goldfish.

ABSTRACT: The circadian system controls temporal homeostasis in all vertebrates. The light-dark (LD) cycle is the most important zeitgeber ("time giver") of circadian system, but feeding time also acts as a potent synchronizer in the functional organization of the teleost circadian system. In mammals is well known that food intake during the rest phase promotes circadian desynchrony which has been associated with metabolic diseases. However, the impact of a misalignment of LD and feeding cycles in the entrainment of fish circadian oscillators is largely unknown. The objective of this work was to investigate how a time-lag feeding alters temporal homeostasis and if this could be considered a stressor. To this aim, goldfish maintained under a 12 h light-12 h darkness were fed at mid-photophase (SF6) o

SUBMITTER: Gomez-Boronat M 

PROVIDER: S-EPMC6290069 | biostudies-literature | 2018

REPOSITORIES: biostudies-literature