Ontology highlight
ABSTRACT:
SUBMITTER: Rametse CL
PROVIDER: S-EPMC6290331 | biostudies-literature | 2018
REPOSITORIES: biostudies-literature
Rametse Cosnet L CL Adefuye Anthonio O AO Olivier Abraham J AJ Curry Lyle L Gamieldien Hoyam H Burgers Wendy A WA Lewis David A DA Williamson Anna-Lise AL Katz Arieh A AA Passmore Jo-Ann S JS
Frontiers in immunology 20181204
Genital inflammatory cytokine responses increase HIV risk. Since male partner semen is a complex mixture of immune-modulatory prostaglandins and cytokines, we hypothesized that exposure to semen may influence genital inflammation in women. Here, we investigated cytokine response kinetics of cervical cells following stimulation with seminal plasma from HIV-negative and HIV-positive men characterized as having low or high concentrations of inflammatory cytokines. Irrespective of the HIV status or ...[more]