The Feasibility Study of Megavoltage Computed Tomographic (MVCT) Image for Texture Feature Analysis.

ABSTRACT: Purpose: To determine whether radiomics texture features can be reproducibly obtained from megavoltage computed tomographic (MVCT) images acquired by Helical TomoTherapy (HT) with different imaging conditions. Methods: For each of the 195 textures enrolled, the mean intrapatient difference, which is considered to be the benchmark for reproducibility, was calculated from the MVCT images of 22 patients with early-stage non-small-cell lung cancer. Test-retest MVCT images of an in-house designed phantom were acquired to determine the concordance correlation coefficient (CCC) for these 195 texture features. Features with high reproducibility (CCC > 0.9) in the phantom test-retest set were investigated for sensitivities to different imaging protocols, scatter levels, and motion fre

SUBMITTER: Gu J 

PROVIDER: S-EPMC6290333 | biostudies-literature | 2018

REPOSITORIES: biostudies-literature