Prevention of Early Postoperative Decline (PEaPoD): protocol for a randomized, controlled feasibility trial.

ABSTRACT:

Background

Delirium is associated with a significantly increased risk of postoperative morbidity and mortality. Furthermore, delirium has been associated with an increased risk of prolonged cognitive deficits and accelerated long-term cognitive decline. To date, experimental interventions for delirium have mainly focused on alternative pharmacologic and behavioral strategies in the postoperative period. Few studies have examined whether proactive strategies started before surgery can prevent delirium or reduce its sequelae. Neurocognitive training programs such as Lumosity have been shown to be effective in increasing cognitive performance in both elderly healthy volunteers and patients suffering from a myriad of acute and chronic medical conditions. When initiated in the preoperat

SUBMITTER: O'Gara B 

PROVIDER: S-EPMC6290549 | biostudies-literature | 2018 Dec

REPOSITORIES: biostudies-literature