Altered monetary loss processing and reinforcement-based learning in individuals with obesity.

ABSTRACT: Individuals with obesity are often characterized by alterations in reward processing. This may affect how new information is used to update stimulus values during reinforcement-based learning. Here, we investigated obesity-related changes in non-food reinforcement processing, their impact on learning performance as well as the neural underpinnings of reinforcement-based learning in obesity. Nineteen individuals with obesity (BMI > = 30 kg/m², 10 female) and 23 lean control participants (BMI 18.5-24.9 kg/m², 11 female) performed a probabilistic learning task during functional magnetic resonance imaging (fMRI), in which they learned to choose between advantageous and disadvantageous choice options in separate monetary gain, loss, and neutral conditions. During learning

SUBMITTER: Kube J 

PROVIDER: S-EPMC6290732 | biostudies-literature | 2018 Oct

REPOSITORIES: biostudies-literature