Neural responses to natural and model-matched stimuli reveal distinct computations in primary and nonprimary auditory cortex.

ABSTRACT: A central goal of sensory neuroscience is to construct models that can explain neural responses to natural stimuli. As a consequence, sensory models are often tested by comparing neural responses to natural stimuli with model responses to those stimuli. One challenge is that distinct model features are often correlated across natural stimuli, and thus model features can predict neural responses even if they do not in fact drive them. Here, we propose a simple alternative for testing a sensory model: we synthesize a stimulus that yields the same model response as each of a set of natural stimuli, and test whether the natural and "model-matched" stimuli elicit the same neural responses. We used this approach to test whether a common model of auditory cortex-in which spectrogram-like peripher

SUBMITTER: Norman-Haignere SV 

PROVIDER: S-EPMC6292651 | biostudies-literature | 2018 Dec

REPOSITORIES: biostudies-literature