Osteoarthritis year in review 2017: genetics and epigenetics.

ABSTRACT:

Objective

The purpose of this review is to describe highlights from original research publications related to osteoarthritis (OA), epigenetics and genomics with the intention of recognising significant advances.

Design

To identify relevant papers a Pubmed literature search was conducted for articles published between April 2016 and April 2017 using the search terms 'osteoarthritis' together with 'genetics', 'genomics', 'epigenetics', 'microRNA', 'lncRNA', 'DNA methylation' and 'histone modification'.

Results

The search term OA generated almost 4000 references. Publications using the combination of descriptors OA and genetics provided the most references (82 references). However this was reduced compared to the same period in the previous year; 8.1-2.1% (expressed as a

SUBMITTER: Peffers MJ 

PROVIDER: S-EPMC6292677 | biostudies-literature | 2018 Mar

REPOSITORIES: biostudies-literature