Evaluating the Impacts of Methylsulfonylmethane on Allergic Rhinitis After a Standard Allergen Challenge: Randomized Double-Blind Exploratory Study.

ABSTRACT:

Background

The sulfur-containing compound methylsulfonylmethane (MSM) has been used as a dietary supplement for a variety of reported health benefits. Clinical observations and case studies have indicated that MSM may help alleviate allergic rhinitis; however, this effect has not been evaluated under controlled conditions.

Objective

This study aimed to determine the effects of MSM consumption on allergic rhinitis symptoms after provocation with a standardized allergen.

Methods

We recruited healthy participants with a history of allergic nasal congestion to participate in a randomized, double-blind, adaptive-design study. Participants were administered a standardized allergen in clinic to determine the presence or absence of an allergic response. Participant responses

SUBMITTER: Hewlings S 

PROVIDER: S-EPMC6293242 | biostudies-literature | 2018 Nov

REPOSITORIES: biostudies-literature