Supportive interventions to improve retention on ART in people with HIV in low- and middle-income countries: A systematic review.

ABSTRACT:

Objectives

To determine whether supportive interventions can increase retention in care for patients on antiretroviral therapy (ART) in low- and middle-income countries (LMIC).

Design

Systematic review and meta-analysis.

Methods

We used Cochrane Collaboration methods. We included randomised controlled trials (RCT) and observational studies with comparators conducted in LMIC. Our principal outcomes were retention, mortality and the combined outcome of lost-to-follow-up (LTFU) or death.

Results

We identified seven studies (published in nine articles); six of the studies were from Sub-Saharan Africa. We found four types of interventions: 1) directly observed therapy plus extra support ("DOT-plus"), 2) community-based adherence support, 3) adherence clubs and 4) ex

SUBMITTER: Penn AW 

PROVIDER: S-EPMC6294385 | biostudies-literature | 2018

REPOSITORIES: biostudies-literature