Impact of Opioid Dose Reduction and Risk Mitigation Initiatives on Chronic Opioid Therapy Patients at Higher Risk for Opioid-Related Adverse Outcomes.

ABSTRACT:

Objective

We aimed to determine if opioid risk reduction initiatives including dose reduction and risk mitigation strategies for chronic noncancer pain patients receiving chronic opioid therapy (COT) had a differential impact on average daily opioid doses of COT patients at higher risk for opioid-related adverse outcomes compared with lower-risk patients.

Design

Interrupted time series.

Setting

Group Health Cooperative (GH), a health care delivery system and insurance within Washington State, between 2006 and 2014.

Population

GH enrollees on COT defined as receiving a supply of 70 or more days of opioids within 90 days using electronic pharmacy data for filled prescriptions.

Methods

We compared the average daily morphine equivalent doses (MED) of COT pat

SUBMITTER: Thakral M 

PROVIDER: S-EPMC6294398 | biostudies-literature | 2018 Dec

REPOSITORIES: biostudies-literature