Serum inhibin B concentration as a predictor of age at first menstruation in girls with idiopathic central precocious puberty.

ABSTRACT: OBJECTIVE:To compare the serum inhibin B, anti-Müllerian hormone (AMH) and leptin concentrations in girls with idiopathic central precocious puberty (CPP) to their concomitant characteristics and evaluate the capacity of each of these hormones to predict the age at first menstruation in those who were untreated and who completed their puberty. METHODS:This single-center study included 94 girls selected from a cohort of 493 girls seen between 1981 and 2012 and diagnosed with idiopathic CPP for whom a remaining serum sample collected at the initial evaluation was available. Of these 25 were untreated and completed their puberty. RESULTS- CORRELATIONS AT INITIAL EVALUATION:In the whole cohort the inhibin B concentration displayed significant positive correlations with the age at the onset of

SUBMITTER: Tencer J 

PROVIDER: S-EPMC6294425 | biostudies-literature | 2018

REPOSITORIES: biostudies-literature