Sex differences in long-term outcomes of patients across the spectrum of coronary artery disease.

ABSTRACT:

Background

Patients with nonobstructive coronary artery disease (CAD) have worse outcomes compared with those without CAD; however, few studies have compared the intermediate- and long-term impact of CAD severity as a function of patient sex.

Methods

We evaluated 5-year and long-term all-cause mortality of women and men undergoing elective coronary angiography at a single center by degree of CAD: no CAD (1%-24% stenosis), nonobstructive CAD (25%-69% epicardial stenosis or 25%-49% left main stenosis), or obstructive CAD (epicardial stenosis ≥70% or left main stenosis ≥50%), both overall and after adjusting for baseline clinical risk factors using Cox proportional-hazards models.

Results

Between January 1986 and July 2010, 8,766 women and 11,638 men underwent angiograph

SUBMITTER: Pagidipati NJ 

PROVIDER: S-EPMC6294713 | biostudies-literature | 2018 Dec

REPOSITORIES: biostudies-literature