Super-resolution T2-weighted 4D MRI for image guided radiotherapy.

ABSTRACT: BACKGROUND AND PURPOSE:The superior soft-tissue contrast of 4D-T2w MRI motivates its use for delineation in radiotherapy treatment planning. We address current limitations of slice-selective implementations, including thick slices and artefacts originating from data incompleteness and variable breathing. MATERIALS AND METHODS:A method was developed to calculate midposition and 4D-T2w images of the whole thorax from continuously acquired axial and sagittal 2D-T2w MRI (1.5 × 1.5 × 5.0 mm3). The method employed image-derived respiratory surrogates, deformable image registration and super-resolution reconstruction. Volunteer imaging and a respiratory motion phantom were used for validation. The minimum number of dynamic acquisitions needed to calculate a representative midposition image was in

SUBMITTER: Freedman JN 

PROVIDER: S-EPMC6294732 | biostudies-literature | 2018 Dec

REPOSITORIES: biostudies-literature