Short-term interval aerobic exercise training does not improve memory functioning in relapsing-remitting multiple sclerosis-a randomized controlled trial.

ABSTRACT:

Background

Only few aerobic exercise intervention trials specifically targeting cognitive functioning have been performed in multiple sclerosis.

Objective and methods

This randomized controlled trial with 34 patients in the intervention group (IG) (mean: 38.2 years (±9.6)) and 34 patients in the control group (CG) (mean: 39.6 years (±9.7)) aimed to determine the effects of aerobic exercise on cognition in relapsing-remitting multiple sclerosis (RRMS). The primary outcome was verbal learning assessed by the verbal learning and memory test (VLMT). Patients were randomized to an IG or a waitlist CG. Patients in the IG exercised according to an individually tailored training schedule (with two to three sessions per week for 12 weeks). The primary analysis was carried out using t

SUBMITTER: Baquet L 

PROVIDER: S-EPMC6295157 | biostudies-literature | 2018

REPOSITORIES: biostudies-literature