The impact of pneumococcal vaccination on pneumonia mortality among the elderly in Japan: a difference-in-difference study.

ABSTRACT:

Background

It is plausible that the routine immunization among infants using pneumococcal conjugate vaccine 13 (PCV13) from 2013 and among the elderly using pneumococcal polysaccharide vaccine 23 (PPV23) from 2014 contributed to reducing the pneumonia mortality among the elderly in Japan. The present study aimed to estimate the causal effect of this vaccination on pneumonia mortality, using the available cause-of-death data and employing a difference-in-difference (DID) design.

Methods

Two types of mortality data, that is, prefecture-dependent and age- and gender-specific mortality data, from 2003 to 2017 were retrieved. We used mortality due to malignant neoplasm and heart disease as control groups and employed a DID design with an assumed parallel mortality trend between p

SUBMITTER: Jung SM 

PROVIDER: S-EPMC6295158 | biostudies-literature | 2018

REPOSITORIES: biostudies-literature