Anogenital distance is associated with semen quality but not reproductive hormones in 1106 young men from the general population.

ABSTRACT:

Study question

Is anogenital distance (AGD) associated with semen quality and reproductive hormones in men from the general population?

Summary answer

Short AGD measured from the anus to the base of scrotum (AGDAS) was associated with reduced sperm counts and morphology but not with sperm motility or reproductive hormones.

What is known already

AGD is longer in males than in females. In rodents, AGD is a well-established and sensitive marker of disruption during the masculinization programming window in utero and it has been suggested to be so in humans as well. Therefore, the average AGD would be expected to be shorter in men with poor semen quality, which some studies have confirmed while others have not.

Study design, size, duration

This cross-sectional popu

SUBMITTER: Priskorn L 

PROVIDER: S-EPMC6295959 | biostudies-literature | 2019 Jan

REPOSITORIES: biostudies-literature