The epidemiology and clinical characteristics of myeloproliferative neoplasms in Malaysia.

ABSTRACT:

Background

The evolution of molecular studies in myeloproliferative neoplasms (MPN) has enlightened us the understanding of this complex disease consisting of polycythaemia vera (PV), essential thrombocythemia (ET) and primary myelofibrosis (PMF). The epidemiology is well described in the western world but not in Asian countries like Malaysia.

Materials and methods

This retrospective national registry of MPN was conducted from year 2009 to 2015 in Malaysia.

Results

A total of 1010 patients were registered over a period of 5 years. The mean age was 54 years with male predominance. The ethnic distribution revealed that Chinese had a relatively high weighted incidence proportion (43.2%), followed by Indian (23.8%), Malay (15.8%) and other ethnic groups (17.2%). The types

SUBMITTER: Yap YY 

PROVIDER: S-EPMC6296047 | biostudies-literature | 2018

REPOSITORIES: biostudies-literature