Escherichia coli bacteriuria in pregnant women in Ghana: antibiotic resistance patterns and virulence factors.

ABSTRACT:

Objectives

The relevance of Escherichia coli associated bacteriuria infection in pregnant women is poorly understood, despite these strains sharing a similar virulence profile with other pathogenic E. coli causing severe obstetric and neonatal infections. We characterized and determined the antimicrobial susceptibility, resistance genes and virulence profiles of 82 E. coli isolates associated with asymptomatic bacteriuria in some pregnant in Ghana from February to August 2016 using Kirby-Bauer disc diffusion and polymerase chain reaction.

Results

High levels of antimicrobial resistance were observed to ampicillin (79.3%), tetracycline (70.7%) and cotrimoxazole (59.8%), except for cefuroxime (32.9%). Resistance genes analyses revealed 58.5% were positive for Bla_TEM

SUBMITTER: Forson AO 

PROVIDER: S-EPMC6296117 | biostudies-literature | 2018 Dec

REPOSITORIES: biostudies-literature