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Green synthesis of zero valent colloidal nanosilver targeting A549 lung cancer cell: In vitro cytotoxicity.


ABSTRACT: An eco-friendly green approach was proposed to synthesise stable, cytotoxic colloidal silver nanoparticles (AgNPs) using Momordica charantia (M. charantia) fruit extract. Bioinspired green method adopted for fabrication of AgNPs because of easy, fast, low-cost and benign bioprocess. Phytocomponents played the crucial role in capping, stabilisation and inherent cytotoxic potential of colloidal nanosilver. The physiochemical, crystalline, optical and morphological properties of AgNPs were characterized using UV-vis, FT-IR, XRD, SEM, TEM, EDX and AFM. FT-IR reveals the presence of carbonyl, methyl, polyphenol (flavonoid), primary and secondary amine (protein), carboxyl group, ester as major functional groups over the surface of nanomaterials. Mechanistic pathway for formation an

SUBMITTER: Jha M 

PROVIDER: S-EPMC6296562 | biostudies-literature | 2018 Jun

REPOSITORIES: biostudies-literature