ICU survival and need of renal replacement therapy with respect to AKI duration in critically ill patients.

ABSTRACT:

Background

Transient and persistent acute kidney injury (AKI) could share similar physiopathological mechanisms. The objective of our study was to assess prognostic impact of AKI duration on ICU mortality.

Design

Retrospective analysis of a prospective database via cause-specific model, with 28-day ICU mortality as primary end point, considering discharge alive as a competing event and taking into account time-dependent nature of renal recovery. Renal recovery was defined as a decrease of at least one KDIGO class compared to the previous day.

Setting

23 French ICUs.

Patients

Patients of a French multicentric observational cohort were included if they suffered from AKI at ICU admission between 1996 and 2015.

Intervention

None.

Results

A total of 52

SUBMITTER: Truche AS 

PROVIDER: S-EPMC6297118 | biostudies-literature | 2018 Dec

REPOSITORIES: biostudies-literature