Radiation for ETMR: Literature review and case series of patients treated with proton therapy.

ABSTRACT:

Background and purpose

Embryonal tumors with multilayered rosettes (ETMRs) are aggressive tumors that typically occur in young children. Radiation is often deferred or delayed for these patients due to late effects; proton therapy may mitigate some of these concerns. This study reviews the role of radiation in ETMR and describes initial results with proton therapy.

Materials and methods

Records of patients with embryonal tumor with abundant neuropil and true rosettes (ETANTR), medulloepithelioma (MEP), and ependymoblastoma (EPL) treated with proton therapy at our institution were retrospectively reviewed. A literature review of cases of CNS ETANTR, MEP, and EPL published since 1990 was also conducted.

Results

Seven patients were treated with proton therapy. Their medi

SUBMITTER: Jaramillo S 

PROVIDER: S-EPMC6297264 | biostudies-literature | 2019 Feb

REPOSITORIES: biostudies-literature