BrainEXP: a database featuring with spatiotemporal expression variations and co-expression organizations in human brains.

ABSTRACT:

Summary

Gene expression changes over the lifespan and varies among different tissues or cell types. Gene co-expression also changes by sex, age, different tissues or cell types. However, gene expression under the normal state and gene co-expression in the human brain has not been fully defined and quantified. Here we present a database named Brain EXPression Database (BrainEXP) which provides spatiotemporal expression of individual genes and co-expression in normal human brains. BrainEXP consists of 4567 samples from 2863 healthy individuals gathered from existing public databases and our own data, in either microarray or RNA-Seq library types. We mainly provide two analysis results based on the large dataset: (i) basic gene expression across specific brain regions, age ranges and

SUBMITTER: Jiao C 

PROVIDER: S-EPMC6298050 | biostudies-literature | 2019 Jan

REPOSITORIES: biostudies-literature