Resistance protein Pit interacts with the GEF OsSPK1 to activate OsRac1 and trigger rice immunity.

ABSTRACT: Resistance (R) genes encode intracellular nucleotide-binding/leucine-rich repeat-containing (NLR) family proteins that serve as critical plant immune receptors to induce effector-triggered immunity (ETI). NLR proteins possess a tripartite domain architecture consisting of an N-terminal variable region, a central nucleotide-binding domain, and a C-terminal leucine-rich repeat. N-terminal coiled-coil (CC) or Toll-interleukin 1 receptor (TIR) domains of R proteins appear to serve as platforms to trigger immune responses, because overexpression of the CC or TIR domain of some R proteins is sufficient to induce an immune response. Because direct downstream signaling molecules of R proteins remain obscure, the molecular mechanisms by which R proteins regulate downstream signaling a

SUBMITTER: Wang Q 

PROVIDER: S-EPMC6298070 | biostudies-literature | 2018 Dec

REPOSITORIES: biostudies-literature