Clinical and Echocardiographic Correlates of Left Atrial Function Index: The Framingham Offspring Study.

ABSTRACT:

Background

Left atrial (LA) remodeling is a predictor of cardiovascular disease (CVD). We performed measurement of the LA function index (LAFI), a composite measure of LA structure and function, in a community-based cohort and here report the distribution and cross-sectional correlates of LAFI.

Methods

In 1,719 Framingham Offspring Study participants (54% women, mean age 66 ± 9 years), we derived LAFI from the LA emptying fraction, left ventricular (LV) outflow tract velocity time integral, and indexed maximal LA volume. We used multivariable linear regression to assess the clinical and echocardiographic correlates of LAFI adjusting for age, sex, anthropometric measurements, and CVD risk factors.

Results

The average LAFI was 35.2 ± 12.1. Overall, LAFI declined with ad

SUBMITTER: Sardana M 

PROVIDER: S-EPMC6298216 | biostudies-literature | 2017 Sep

REPOSITORIES: biostudies-literature