Effects of regular endurance exercise on GlycA: Combined analysis of 14 exercise interventions.

ABSTRACT:

Background and aims

GlycA is a relatively new biomarker for inflammation as well as cardiometabolic disease risk. However, the effect of exercise on GlycA is largely unknown. Therefore, the purpose of this study was to examine the effects of regular exercise on the inflammatory marker GlycA across seven studies and 14 exercise interventions.

Methods

Nuclear magnetic resonance spectroscopy, specifically signal amplitudes originating from the N-acetyl methyl group protons of the N-acetylglucosamine residues on the glycan branches of glycoproteins, was used to quantify GlycA concentrations. GlycA was measured before and after completion of an exercise intervention in 1568 individuals across seven studies and 14 exercise interventions. Random effects inverse variance weighting m

SUBMITTER: Barber JL 

PROVIDER: S-EPMC6298739 | biostudies-literature | 2018 Oct

REPOSITORIES: biostudies-literature