Continuously Updated Estimation of Heart Transplant Waitlist Mortality.

ABSTRACT:

Background

Heart transplant allocation in the United States is made on the basis of coarse tiers, defined by mechanical circulatory devices and therapy for advanced heart failure, updated infrequently as a patient's condition deteriorates. Thus, many patients die awaiting heart transplantation. What is needed is a tool that continuously updates risk of mortality as a patient's condition changes to inform clinical decision making.

Objectives

This study sought to develop a decision aid that aggregates adverse events and measures of end-organ function into a continuously updated waitlist mortality estimate.

Methods

From 2008 to 2013, 414 patients were listed for heart transplantation at Cleveland Clinic, Cleveland, Ohio. The endpoint was waitlist death. Pre-listing patie

SUBMITTER: Blackstone EH 

PROVIDER: S-EPMC6298792 | biostudies-literature | 2018 Aug

REPOSITORIES: biostudies-literature