Acute histoplasmosis in immunocompetent travelers: a systematic review of literature.

ABSTRACT:

Background

Histoplasmosis is a fungal infection highly endemic in the American continent. The disease can be severe in immunocompromised subjects. In immunocompetent subjects the clinical manifestations are variable. Aim of this work was to review the cases of acute histoplasmosis in immunocompetent travelers reported in literature.

Methods

A systematic review of literature was conducted. Electronic search was performed in Pubmed and LILACS. Two reviewers independently extracted data on demographic, clinical and radiological features, and treatment. Cases were classified according to Wheat's definitions.

Results

Seventy-one studies were included in the analysis, comprising a total of 814 patients. Twenty-one patients diagnosed at the Centre of Tropical Diseases, Negra

SUBMITTER: Staffolani S 

PROVIDER: S-EPMC6299618 | biostudies-literature | 2018 Dec

REPOSITORIES: biostudies-literature