Estimating severity of influenza epidemics from severe acute respiratory infections (SARI) in intensive care units.

ABSTRACT: BACKGROUND:While influenza-like-illness (ILI) surveillance is well-organized at primary care level in Europe, few data are available on more severe cases. With retrospective data from intensive care units (ICU) we aim to fill this current knowledge gap. Using multiple parameters proposed by the World Health Organization we estimate the burden of severe acute respiratory infections (SARI) in the ICU and how this varies between influenza epidemics. METHODS:We analyzed weekly ICU admissions in the Netherlands (2007-2016) from the National Intensive Care Evaluation (NICE) quality registry (100% coverage of adult ICUs in 2016; population size 14 million) to calculate SARI incidence, SARI peak levels, ICU SARI mortality, SARI mean Acute Physiology and Chronic Health Evaluation (APACHE) IV score,

SUBMITTER: van Asten L 

PROVIDER: S-EPMC6299979 | biostudies-literature | 2018 Dec

REPOSITORIES: biostudies-literature