Noncontact recognition of fluorescently labeled objects in deep tissue via a novel optical light beam arrangement.

ABSTRACT: To date, few optical imaging systems are available in clinical practice to perform noninvasive measurements transcutaneously. Instead, functional imaging is performed using ionizing radiation or intense magnetic fields in most cases. The applicability of fluorescence imaging (e.g., for the detection of fluorescently labeled objects, such as tumors) is limited due to the restricted tissue penetration of light and the required long exposure time. Thus, the development of highly sensitive and easily manageable instruments is necessary to broaden the utility of optical imaging. To advance these developments, an improved fluorescence imaging system was designed in this study that operates on the principle of noncontact laser-induced fluorescence and enables the detection of fluorescence from de

SUBMITTER: Hien A 

PROVIDER: S-EPMC6300195 | biostudies-literature | 2018

REPOSITORIES: biostudies-literature