Impact of treatment with direct-acting antivirals on anxiety and depression in chronic hepatitis C.

ABSTRACT: BACKGROUND AND AIM:Treatment of hepatitis C with direct-acting antiviral agents (DAA) has few side effects. Although pivotal studies suggested that DAA were safe in patients with psychiatric diseases who could not be treated with previous antiviral therapies, their effects on anxiety and depression have not yet been analysed in clinical practice. The aim of our study was to analyse anxiety and depression in the setting of DAA treatment in a clinical practice series. METHODS:All patients starting DAA treatment between November 1, 2014 and October 31, 2015 were eligible. Patients completed the Hospital Anxiety and Depression scale at different times during treatment. The results were plotted on line graphs and evaluated using a linear regression model with repeated measures. RESULTS:One hund

SUBMITTER: Gallach M 

PROVIDER: S-EPMC6300319 | biostudies-literature | 2018

REPOSITORIES: biostudies-literature